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encoded by ABCC1 gene) (Farina and Aschner 2019

Matarredona et al., 1997)

Ustekinumab (anti-p40), targeting this pathway, induces and maintains remission in both CD and UC, with high steroid-free remission rates in children and adolescents at 26 and 52 weeks, and long-term safety profiles that are favorable [316]