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Abstract Introduction Progressive Familial intrahepatic cholestasis (PFIC) are rare disorders of bile acid (BAs) secretion and transport with a genetic background

Sulfated and nonsulfated bile acids in urine, serum, and bile of patients with hepatobiliary diseases

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In addition, selective depletion of Tie-2 expression in macrophages induces tumor vascular normalization and the regression of established tumors, supporting the critical role of TEMs during tumor angiogenesis 56,57