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This regulation by mTORC1 is essential for normal cellular functions and implicates its dysregulation in various diseases, including cancer, where unchecked cellular growth and protein synthesis drive tumor progression

Distribution of cyclooxygenase-3 (COX-3) in rat nervous system

In practice, this means an enteral-first strategy after haemodynamic stabilisation, stepwise advancement of protein delivery toward guideline-level targets, avoidance of excessive early metabolic load, and repeated reassessment of tolerance and target attainment (2, 16, 51, 56)

doi: 10.1128/iai.00614-21 179 WanfordJ

Either way, those greys are a symbol of life

Patients with NCPH who developed cirrhosis and decompensated were excluded