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Description

YAP, but Not RSPO-LGR4/5, signaling in biliary epithelial cells promotes a ductular reaction in response to liver injury

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Notably, evidence supports its involvement in regulating IOP and AH dynamics, as melatonin receptors are found in various ocular tissues (65, 66)

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This phenotype is indicative of an adaptive, dedifferentiated state, distinct from the more stable melanogenic profile observed on both COL I and COL IV, and suggests that FN may act as a cue for reprogramming MC identity

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