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Selective androgen receptor modulators (SARMs): A novel approach to androgen therapy for the new millennium

While N-(4-hydroxyphenyl) retinamide (4-HPR), a derivative of RA, is a potent chemopreventive and antiproliferative agent against various cancers [200, 201]

In vitro study using human vascular endothelial cells further confirmed the increased mRNA and protein expressions of VEGFR2 but not VEGF-A

Methods Ethical statement All protocols for animal studies were approved by Animal Ethics Committee at the Institute of Radiation Medicine of the Chinese Academy of Medical Sciences (CAMS) (No.IRM-DWLL-2021177)