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Upregulation or modulation of genes involved in the ergosterol biosynthetic pathway (ERG family), as well as modifications to sterol content, may alter the binding or activity of polyenes, and in the case of azoles, change the abundance of the target enzyme (lanosterol 14-demethylase), which affects its activity

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Oxidative Medicine and Cellular Longevity 2019, 3150145.CrossRefGoogle ScholarPubMed Arteel, GE and Sies, H (2001) The biochemistry of selenium and the glutathione system