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Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene

These same pathways that promote fat burning also antagonize insulin

It is found in about 0.1% of the overall population, but it is much more common in older adults

Miura and Thomas Jr, 1995

Over and above their role in the stimulation of metabolism, they also aid in quicker stable energy and thermogenesis burns resulting in more efficient calorie burning and effective reduction of weight