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To mimic the trimerized conformation of the native SARS-CoV-2 spike glycoprotein more closely, they fused naturally trimerized human resistin to the spike ectodomain to generate a stable trimer protein antigen called SmT1

The combination of long operative times, reduced mobility in the early recovery period, and the hypercoagulable state that often accompanies obesity and significant weight loss creates a perfect storm

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