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In some patients, the emotional pattern is that of mania or euphoria

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FIGURE 2 Given the close proximity of the TME to cancer cells targeted by treatment, the TME is invertedly changed during cancer treatment

Our results are consistent with recent studies in transformed cell systems where broad redox stress protection is afforded by cell cycle exit, which reroutes metabolic pathways away from translation and anabolic metabolism and toward resource conservation (Conlon et al, 2021

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