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However, following administration of the ferroptosis inhibitors liproxstatin-1 or ferrostatin-1, the levels of inflammatory factors and ROS are reduced, endogenous antioxidant pathways related to Nrf2, HO-1, and NQO1 are upregulated, transforming growth factor- expression is downregulated, and iron ptosis is reduced in lung tissue [107]

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doi: 10.1016/j.parkreldis.2019.01.010 197

Benefits in treating cancer The antioxidant effects of milk thistle may have anti-neoplastic effects

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