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Stabler 24 Patients with severe abnormalities should receive injections of 1000 g at least several times per week for 1 to 2 weeks, then weekly until clear improvement is shown, followed by monthly injections

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As a result, patients may benefit from more accurate and personalised management strategies

Kypreos KE, Karagiannides I, Fotiadou EH, Karavia EA, Brinkmeier MS, Giakoumi SM, et al

Non-stimulant and well-tolerated for long-term use