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doi: 10.1021/acs.jmedchem.7b00389

2015 Apr;63(4):636-40

To prevent or manage vitamin B12 deficiency, incorporating B12-rich foods or supplements into the diet is recommended

Understanding Vitamin B12: What It Is and Why It Matters Vitamin B12 is key for our bodies

It means that as a standalone oral therapy at the tested doses, it did not produce the magnitude of weight loss that pharmaceutical companies require for commercial viability