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For instance, the secretion of interferon gamma (IFN-) by CD8+ T cells has been shown to down-regulate the expression of SLC3A2 and SLC7A11 in tumor cells, leading to a disruption in cystine uptake ( Myeloid-derived suppressor cells (MDSCs) express the transporter SLC7A11, which selectively transports cystathionine but does not export cysteine

The detrimental effects of B12 deficiencysuch as hyperhomocysteinemia and impaired methylationare well-established and can negatively impact oocyte quality and embryo viability [19, 20], which is consistent with the lower pregnancy rates we observed at low B12 levels

We used the GSH and GSSG Assay Kit and followed the product instructions to determine GSH levels

The molecular mechanisms of pancreatic -cell glucotoxicity: recent findings and future research directions

[DOI] [PubMed] [Google Scholar] 140.Luetic K., Sucic M., Vlainic J., Halle Z.B., Strinic D., Vidovic T., Luetic F., Marusic M., Gulic S., Pavelic T.T., et al