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All differential metabolites/biomarkers identified were used as an input set for pathway analysis

This means that LH no longer stimulates the Leydig cells of the testes to produce Testosterone, and correspondingly, FSH no longer stimulates the Sertoli cells to produce sperm

The trans-sulfuration pathway is a critical component in the synthesis of glutathione, which is involved in the production of reactive oxygen species in cancer stem cells

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