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Furthermore, TNF, IFNG, IL17A, IL6, NFKBIA, and TLR4 were predicted as the top upstream negative regulators of these changes

In contrast, Doxorubicin-senescent cells were effectively cleared

A previous study demonstrated that MRPS27 and NDUFS3 tended to form misfolded aggregates when the activity of mitochondrial proteostasis-maintaining machinery was inhibited 23