10.1074/jbc.M110.139824 178 MatuteJ
Frago LM, Paeda C, Dickson SL, Hewson AK, Argente J, Chowen JA
Gut (2006) 55(2):20511
Moderate instability promotes adaptation by enabling oncogene amplifications (e.g., ERBB2, CCND1, MYC) or loss of tumor suppressor loci, facilitating therapeutic escape, whereas excessive instability compromises viability

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The neural disruptions shared by PTSD include asymmetrical white matter tract abnormalities and gray matter changes in the prefrontal cortex (PFC), hippocampus, and basolateral amygdala (BLA