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10.3831/KPI.2022.25.4.390 124 IsidorovV.ZalewskiA.ZambrowskiG.SwiecickaI

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What a Meaningful KLOW COA Should Include Complete chemical name and sequence for every component Declared salt or counterion for KPV, BPC-157 and TB-500 Confirmation of N-terminal acetylation for TB-500 Confirmation that TB-500 is not full thymosin beta-4 GHK-to-copper ratio or copper-assay information Batch-specific mass-spectrometry data Tandem-MS sequence evidence where appropriate Component-specific quantitative assay Measured blend ratio Raw chromatograms rather than a purity number alone Related-substance and degradation-product results Finished-vial content uniformity Stability results for the actual four-component mixture Laboratory identity and scope of accreditation A clear list of tests not performed Why 99% Purity Is Not Enough A single purity percentage may describe only one chromatographic peak or one raw material

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