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In view of the pivotal role played by GSH in redox system and the relationship between oxidative stress and autophagy 68 , it is conceivable that GSH depletion-induced oxidative stress and lipid peroxidation may be a key point linking ferroptosis and autophagy in RPE cells

DNA sensing by the cGAS-STING pathway in health and disease

For expression of the redox probes, mutant strains (Suppl

The connection between epigenetics and food shows just how powerful daily choices can be for your future health

Using available RNAseq datasets of AD mouse models, AD patients and age-matched controls, we analyzed which of the 44 ferroptosis-related genes are differentially expressed in AD (Supplementary Table 1)

Rosas, I