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NMP can lower lactate levels during hepatic perfusion in vitro , maintain hepatic metabolic activity, and lower the risk of early allograft dysfunction (151, 152)

Hence, HSF1 emerges as a major orchestrator of cellular stress response pathways

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Nat Chem Biol 19 , 815824 (2023)

It acts as a powerful prebiotic-like agent, significantly increasing the abundance of SCFA-producing bacteria and enriching Akkermansia muciniphila, a keystone bacterial species famous for enhancing protective mucus production in the gut

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