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If your body isnt absorbing enough vitamin B12 from your diet or a multivitamin, you may experience symptoms such as: Fatigue Muscle weakness Constipation Loss of appetite Irritability or depression Memory problems Insufficient B12 can also cause numbness or tingling in your hands and feet, as well as balance problems

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if too lipophilic, the drug is not soluble enough to cross the water layer adjacent to the cell

Most people absorb enough natural B12 that they dont have to worry about additional supplements, but for those with poor nutrition, stomach problems or cancer, B12 can be hard for the body to process

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Most patients benefit from weekly or biweekly sessions initially, then transition to monthly maintenance