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Randomized controlled trials confirm that daily vitamin E supplementation effectively slows cognitive decline in mild-to-moderate AD patients, supporting its role as a disease-modifying agent (246)

6.3 Vitamin B12 Deficiency Vitamin B12 deficiency represents a critical confounding factor in the diagnosis of DPN, as neuropathy itself is fundamentally a diagnosis of exclusion requiring the elimination of other potential etiologies [157]

[231] Subsequently, the measure was adopted across multiple quality reporting programs including the Hospital Inpatient Quality Reporting Program (86 FR 45374), the Inpatient Psychiatric Facility Quality Reporting Program (86 FR 42633 through 42640), the Hospital Outpatient Quality Reporting Program (86 FR 63824 through 63833), the PPS-Exempt Cancer Hospital Quality Reporting Program (86 FR 45428 through 45434), the Ambulatory Surgical Center Quality Reporting Program (86 FR 63875 through 63883), the Long-Term Care Hospital Quality Reporting Program (86 FR 45438 through 45446), the Skilled Nursing Facility Quality Reporting Program (86 FR 42480 through 42489), the End-Stage Renal Disease Quality Incentive Program (87 FR 67244 through 67248), and the Inpatient Rehabilitation Facility Quality Reporting Program (86 FR 42385 through 42396)

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The downstream targets of Nrf2 can be classified into three categories, which are the regulation of iron metabolism, intermediary metabolism, and glutathione synthesis/metabolism (Kang et al., 2021)

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