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nucleatum colonization accelerates breast cancer metastasis, highlighting its systemic oncogenic potential ( 5 Progress of single agents for anticancer and antibacterial activities The interdependent relationship between tumor cells and microbes presents a formidable obstacle, making it challenging to entirely halt tumor growth and recurrence through the exclusive use of anticancer treatments or antibacterial medications (Yadav et al., 2023)

Chronic fractalkine administration improves glucose tolerance and pancreatic endocrine function

serious effects are rare under supervision

LAM, a typical virulence factor of Mycobacterium tuberculosis, can mediate the MAPK pathway and induce the expression of IL-10 and IL-12 through the differential activation of p38 MAPK and ERK1/2, thereby synergistically regulating the inflammatory microenvironment of host cells in conjunction with TLR2 (44, 72)

Patil SP, Wang J, Song Y, Noone S, Yang N, Wallenstein S et al (2011) Clinical safety of Food Allergy Herbal Formula-2 (FAHF-2) and inhibitory effect on basophils from patients with food allergy: extended phase I study

However, one study investigated non-BRCA1/2 gene abnormalities, and found that they confer sensitivities to PARP inhibition comparable to those observed with BRCA1/2 mutations (147)