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The total Akt expression level was unchanged, while the expression level of phosphorylated Akt (pAkt) was up-regulated with the overexpression of RRM2 , suggesting that RRM2 could be involved in the regulation of phosphorylation activation of Akt, which was consistent with the findings in other cancer types

doi: 10.1093/jas/skae065, 141

There are certain brain disorders that have accelerated neuro-degeneration that give us clues

References 1.Zhang Y., Cai Y., Shi M., Jiang S., Cui S., Wu Y., Gao X.H., Chen H.D

& Marson, L

The mean age, median BMI, and mean WC at baseline were 6210 years, 26.36.0 kg/m, and 91.312.2 cm, respectively