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doi: 10.1016/j.tifs.2019.03.026

Pharmaceuticals (basel) 14:8 Ankam S, Lim CK, Yim EK (2015) Actomyosin contractility plays a role in MAP2 expression during nanotopography-directed neuronal differentiation of human embryonic stem cells

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Collectively, these findings establish epigenetic modifications as pivotal mediators of cellular responses to heat stress, enabling both dynamic adaptation and heritable changes in gene expression without altering the underlying DNA sequence (Wang and Ibeagha-Awemu, 2020)

Compared to conventional pharmaceuticals, natural bioactive constituents from TCM can mitigate oxidative stress in the nervous system through multiple pathways while exhibiting a lower incidence of adverse reactions (14, 23)