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Elevated serum levels of Se-binding protein 1, an autoantibody produced by the ovary, has been reported in women with unexplained intertility and premature ovarian failure (1, 10)

4 intestinal microecology and intestinal immunity The inflammatory response in IBD originates from the activation of innate immune cellsincluding macrophages, dendritic cells, neutrophils, natural killer cells, and innate lymphoid cellswhich release cytokines, chemokines, and antimicrobial peptides