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Long-term IV administration (12 months) of l-carnitine (2 g/day) to patients undergoing hemodialysis resulted in increased serum and muscle carnitine levels, together with hypertrophy and predominance of type I fibers [43] in the muscle

2011;6(11):e26747

As such, this type of adaptive platform trial allows researchers to utilize data connectivity within the trial to answer many questions concurrently, while testing different drug paradigms, without wasting tremendous resources [130]

This could also explain why SCID mice, lacking T and B cells, are able to develop continuous spirochetemia (Wagemakers et al., 2016)

FASEB J 25(S1):782.8-782.8

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