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89 Role of ferroptosis in human diseases Increasing evidence has shown that ferroptosis has an important role in many biological and pathological processes and is involved in the onset and progression of multiple human diseases (Fig

The N-terminal domain of GSDMD (GSDMD-NT) has high affinity for acidic phospholipids, phosphatidylserine, and cardiolipin, which are rich in the inner leaflet of the plasma membrane and in the mitochondrial membrane (80)

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