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Cellular iron status influences the functional relationship between microglia and oligodendrocytes

(B) Ratio between H 2 O 2 production and O 2 consumption by isolated mitochondria under the same conditions as panel A

Maleate, Prochlorperazine 5

MMPs, particularly MMP-9, and proteins such as HMGB1 have also been implicated in BBB breakdown, highlighting the need for further research into these pathways as potential therapeutic targets for AD [184,203,204]