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The authors also noted that further optimisation was needed, including work relating to high clearance in mice and off-target activity against monoamine oxidase A

The NHS treatment page lays it out clearly: Loading phase (no neurological symptoms): 1mg every other day for two weeks, or until symptoms stop improving

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It also improved the proliferative and secretory functions of fibroblasts and reversed morphological abnormalities of senescent cells (such as flattened cell shape, enlarged volume, and nuclear pyknosis)