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Accelerated blood clearance of lipid nanoparticles entails a biphasic humoral response of B-1 followed by B-2 lymphocytes to distinct antigenic moieties

10.1097/CCM.0000000000002772 16

2012a;7:44758

We then used a network pharmacology technique to design gene networks to investigate the related pathways and biological processes, which showed the candidate NPs primarily acted through key signaling pathways, specifically the hsa04010: MAPK signaling pathway