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This innovative delivery system rapidly increases circulatory B12 levels and achieves optimal circulatory vitamin B12 status without causing any GI or other side effects

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B12 IV Dose Recommendations The amount of vitamin B12 for IV use depends on how bad the deficiency is and the patients health

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A randomized, double-blind, placebo-controlled trial in 153 older adults taking the antidepressant citalopram found daily supplementation with 500 g vitamin B 12 , 2 mg of folic acid, and 25 mg of vitamin B6 for one year did not reduce the severity of depressive symptoms but increased the response to drug treatment and helped to prevent symptom relapse (112), suggesting B-vitamin supplementation might provide some benefit as an adjunct therapy