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Inhibition of lipopolysaccharide-mediated human monocyte activation, in vitro , by alpha1-antitrypsin

Icaritin was also reported to decrease intratumoral and splenic MDSCs, which are immunosuppressive cells dampening T cell cytotoxicity

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4.1.1 BCL family inhibitors The BCL family consists of proteins such as BCL-2, BCL-XL, and MCL-1, serving both proapoptotic and pro-survival functions [101]

The T cells, with high expression of CD161 and natural killer (NK)-cell associated markers CD56, CD16 and CD336 (NKp44) indicative of a cytotoxic phenotype, are more abundant in fibrotic biopsies than in nonfibrotic kidney tissue [123]