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The priming signal involves the upregulation of NLRP3 expression and the synthesis of proinflammatory cytokines such as TNF- and IL-1, typically mediated by nuclear factor kappa B activation in response to inflammatory stimuli

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Figure 4 As can be seen from Figure 4A, the AgNPs solution did not show any obvious IR absorption peaks, indicating that the solution has a low background signal and can be used as a SEIRA-enhanced substrate