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Loss of gut microbiota alters immune system composition and cripples Postinfarction cardiac repair

Research examines its effects on NNMT activity, NAD+ homeostasis, metabolic pathway utilization, energy expenditure, and adipose-tissue endpoints independent of feeding-behavior changes

doi: 10.1073/pnas.1505662112 273 KaurAWebsterMRMarchbankKBeheraRNdoyeAKugelCH3rdet al

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When GSH is consumed and feedback inhibition is lost, availability of cysteine as a precursor can become the rate-limiting factor

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