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The major physiological and molecular features of Candida persister cells are summarized in Table 3

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, Functioning as a gas transmitter and signaling molecule, H 2 S mediates cytoprotection against apoptosis through dual mechanisms: direct neutralization of cytotoxic reactive species (e.g., ROS and peroxynitrite) and enhanced expression of endogenous antioxidants (including superoxide dismutase, glutathione, and N-acetylcysteine)