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Individual responses vary considerably based on baseline neurological status, dose, and protocol structure

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Using optogenetics, that uses light to activate certain parts of the brain, they triggered specific patterns of brain activity in sleep-deprived mice that normally occur during sleep

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IMPORTANT : Pinealon and Epitalon are identified as research compounds

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Interestingly, intranigral injection of VEGF, a potent BBB disruptor, could mimic several histopathological hallmarks found in PD [301]

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