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In the secret shopper study, when medical spas were asked about the potential risks of IV therapy, just 24 percent offered any information about what could go wrong

Abbreviations HMs: Heavy metals Al: Aluminium Cd: Cadmium Mn: Manganese Pb: Lead Cr: Chromium ROS: Reactive oxygen species PCs: Phytochelatin HSPs: Heat shock proteins Ca: Calcium Mo: Molybdenum CAT: Catalase H 2 O 2 : Hydrogen peroxide APX: Ascorbate peroxidase AR: Arsenate reductase S: Sulphur SNP: Sodium nitroprusside JA: Jasmonic acid As: Arsenic Cu: Copper Co: Cobalt Ni: Nickel Hg: Mercury Mg: Magnesium GSH: Glutathione MT: Metallothionein (P): Phosphorus EL: Electrolytic leakage O 2 : Superoxide SOD: Superoxide dismutase MDA: Malondialdehyde GR: Glutathione reductase Se: Selenium Si: Silicon NPs: Nanoparticles RWC: Relative water content References Abbas S, Basit F, Tanwir K et al (2023) Exogenously applied sodium nitroprusside alleviates nickel toxicity in maize by regulating antioxidant activities and defense-related gene expression

Nat Prod Res 35(12):20442050 Shin D, Kwon HY, Sohn EJ, Nam MS, Kim JH, Lee JC, Ryu SY, Park B, Kim SH (2015) Upregulation of death receptor 5 and production of reactive oxygen species mediate sensitization of PC-3 prostate cancer cells to TRAIL induced apoptosis by vitisin A

Dietary Cu 2+ is reduced to Cu + by STEAP or DCYTB and then imported through the high-affinity copper transporter CTR1 (SLC31A1) (Figure 3)

the signal amplifying phase, where further inflammatory processes and apoptosis occur

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