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Description

Wu T, Tang M

McLane, L

Competitive inhibition: Some drugs may share the same P-450 specificity and thus competitively block their biotransformation

Several of these, including proteoglycan core proteins, sialo-glycoproteins, surface glycoproteins, and glycosaminoglycans (GAGs), constitute endothelial glycocalyx and are essential for tissue integrity (34)

These lipid species are actively secreted (via exosomes or free diffusion) or passively released through necrosis, creating a lipid-rich TME that directly modulates immune cell fate and function