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Population analysis further showed that SLO-MO neuronsa brainstem path integrator known to encode positional information through persistent activitydisplayed both reduced neuron numbers and shortened activity time constants

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Cell cultures Two cell lines of fibroblasts derived from patient skin biopsies (P1 and P2) and two age- and sex-matched controls fibroblast cell lines from healthy volunteers (C1 and C2) were grown in Dulbeccos modified Eagles medium (DMEM) (Gibco, ThermoFisher Scientific, Waltham, MA, USA) supplemented with 10% FBS (Gibco, ThermoFisher Scientific, Waltham, MA, USA), 100 mg/ml penicillin/streptomycin

PMID: 153 TaherizadehNGhazalianFShirvaniHGholamiMAbednatanziH

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