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Numerous studies have indicated that in scenarios of iron overload, there is an increase in mitochondrial stress, which results in mitochondrial fragmentation and a disruption of the fission and fusion [68, 130]

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Targeting GPX4 increases sensitivity to palbociclib in ER+ breast cancer cell lines The screen data suggested that CDK4/6 inhibition may create a GPX4-dependent state where cells rely on GPX4 to avoid ferroptosis

GA is commonly found in fruits and vegetables, such as grapes, bananas, mushrooms, and olives, and can be obtained from non-sugar gallates in our diet (Habibi et al., 2016

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