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doi: 10.1172/jci.insight.136215 147 BosPDZhangXHNadalCShuWGomisRRNguyenDXet al

several reports detail several taxa that produce endogenous ethanol, as observed in experimental models [51, 179], adult patients with MASLD [160], and even young children with metabolic dysfunction-associated steatohepatitis (MASH) [180]

Thus, the complex heme biosynthesis pathway both starts and ends in mitochondria, although the benefits conferred by this elaborate spatial segregation remain unclear