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[72] co-cultured ADMSCs with degenerative NP cells, and explored the involved signalling pathways and regulatory networks through the lncRNA and mRNA expression profiles in the system

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Reviewer #3 (Remarks to the Author) This manuscript tackles an important aspect of debilitating diseases such as newborn brain injury and multiple sclerosis, that of identifying therapeutic agents which promote remyelination in injury

Discussion Our results provide evidence that intrastromal implantation of a cell-free bioengineered collagen-based material can be a safe and feasible means to reverse the pathologic corneal thinning and deformation in advanced keratoconus

When the container is three-quarters full, seal it and dispose according to local regulations