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An important methodological question is whether the flat concentration-time profiles of epinephrine and norepinephrine under our experimental conditions truly reflect the absence of adsorption or could be masked by analytical or preanalytical artefacts

As we further understand pathophysiological nuances, pharmacological approaches may provide improved symptom control

We have also presented advanced technologies for the fabrication of smart biomaterials and proposed strategies and challenges for future clinical translation of smart biomaterials, emphasizing AI-driven therapeutic frameworks for personalized biomaterial design

Future studies may investigate expanding inclusion criteria to include decompensated liver disease and other co-morbid conditions

Continued research, user feedback, and clinical studies will shed more light on its efficacy, safety profile, and whether it can truly stand as a formidable contender to MK-677

Nevertheless, the highest fluorescence was observed in the RhB-Lip group rather than in the RhB-Lip-Gel group, which suggested that the hydrogel delayed the release of its content under the same conditions