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The clinical significance of a one-point change in NTSS-6 score among patients with moderate or severe symptoms in the Metanx group is unclear.(11) Although Yaqub et als study showed symptom improvement in the methylcobalamin group, the results were not compared with the placebo group.(12) Furthermore, Farvid et als study showed no difference in the improvement of symptoms between the vitamin B and non-vitamin B groups

McGrath, The Evolution of Resorts and Guest Ranches in Greater Phoenix, (unpublished manuscript, 1973, Arizona Collection MSM-132, Hayden Library, Arizona State University), 5

Also, inform your doctor about your complete medical history and all other medicines, supplements, or vitamins you are taking, as they may interact with the treatment

Stay well-hydrated by sipping water throughout the day, as adequate hydration helps maintain normal saliva production and can reduce taste disturbances

Prendre la B12 au cours d'un repas pour limiter les troubles digestifs

If you experience unexpected symptoms whilst taking B12, discuss with your GP whether continued supplementation is necessary or whether dose adjustment might help