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BWHS, Black Womens Health Study

60 In cancer cells, complex II activation via METTL1-mediated m7G tRNA modification and SDHAF4 upregulation drives mitochondrial OXPHOS and gastric cancer progression, 61 whereas complex II activity is downregulated by evolutionarily conserved selenoprotein O (SELENOO)-mediated AMPylation of SDHA, promoting melanoma metastasis through modulation of oxidative stress responses

[DOI] [PubMed] [Google Scholar] 632.Ma E., Chen P., Wilkins H.M., Wang T., Swerdlow R.H., Chen Q

the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists

SIRT2 expression was then knocked down by shRNA in SIRT2-high cell lines (CAKI-1 and A498), and cellular GSH level were found to be significantly reduced (Figs