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The synthesis of compound 18 To a solution of 3-chloro-acetanilid (600 mg, 2.95 mmol) in Ac 2 O/AcOH (4/1, v/v, 5 mL) was added HNO 3 (445.82 mg, 5.90 mmol) dropwise at 0 C

doi:10.1097/HJH.0000000000000634

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