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24 Deficiency of FAH would not be expected to result in elevated blood tyrosine, since FAH is five steps removed from the initial catabolic step in tyrosine degradation (Figure 1)

Labbe SM et al

Exclusion criteria included conference abstracts, editorials, non-English papers, and studies unrelated to the nervous system or lacking mechanistic or therapeutic focus

Sadhu SS, Xie J, Zhang H, Perumal O, Guan X

Apr 24 2021;11(5)doi:10.3390/jpm11050342 Cetinel S, Ercan F, Sirvanci S, et al

We've synthesized research data from multiple institutions and observed consistent patterns: researchers who time administration around AMPK pathway activation windows report significantly more robust metabolic markers than those using concurrent dosing