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In the present study, Rd is firstly identified as a novel endothelial barrier remediation, effectively alleviating the acute BRB breakdown in a VEGF-induced mouse model and the chronic vascular leakage in a STZ-induced DR model

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For example, ACLY is needed for the production of the eicosanoid prostaglandin E2 (PGE 2 ) in response to LPS or TNF- stimulation in phorbol-12-myristate-13-acetate (PMA)-differentiated U937 cells, human monocytic cells from histiocytoma 73

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Archived from the original on 17 August 2017

Nat Commun (2016) 7:13419