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ROS are initiating factor in gastric carcinogenesis in both humans and mice

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(4) S Seiwerth, M Milavic, J Vukojevic, S Gojkovic, et al (2021)

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After demonstrating the transcriptional augmentation of SIRT3 by Rd, C-C and Compound A (C-A) were employed to inhibit AMPK and ERR respectively, and the treatment blocked the enhancing effects of Rd (Fig