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Interestingly, in renal clear cell carcinoma, IDO expressed by neovascularization endothelial cells is an inhibitory factor in tumor growth because it limits the flow of tryptophan from the blood to the tumor or produces tumor toxic substances (Riesenberg et al., 2007)

investigated the effects of administering nerve growth factor (NGF) alongside the transplantation of human umbilical vein-derived mesenchymal stem cell (hUV-MSC) dopaminergic-like cells into the striatum of rats

There is substantial evidence that the STAT3-dependent signaling induces the polarization of macrophages toward the immunosuppressive M2 phenotype [112]

HO-1 expression was significantly reduced during dendritic cell maturation in vitro, which corresponds to the absence of HO-1 expression by mature dendritic cells in human tissues